Welcome Back

Google icon Sign in with Google
OR
I agree to abide by Pharmadaily Terms of Service and its Privacy Policy

Create Account

Google icon Sign up with Google
OR
By signing up, you agree to our Terms of Service and Privacy Policy
Instagram
youtube
Facebook

Research Associate/Senior Research Associate - Adme

2-4 years
Not Disclosed
10 June 28, 2024
Job Description
Job Type: Full Time Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Job Description

Reporting and Team Collaboration

  • Report to the senior team leader.
  • Work with a group of in vitro assay biologists.
  • Learn and coach group members to improve skills and productivity.
  • Conduct day-to-day testing and profiling of compounds in cells/protein-based assays or experiments in a team-oriented environment.
  • Analyze, interpret, draw conclusions, and test new methodologies.
  • Multitask, recognize problems, provide input to solutions, draft reports, and properly document experiments.
  • Present results proficiently within the lab, at project or review meetings, and for other internal/external parties as needed.

Assay Development and Data Analysis

  • Perform all ADME assays.
  • Develop methods and collect data using LC-MS/MS and other modalities (absorbance/fluorescence).
  • Develop new assays for ADME activities.
  • Analyze data from enzyme activities using GraphPad Prism and MS Excel.
  • Analyze MS data using Sciex.

Report Compilation and Collaboration

  • Compile reports and interface with collaborators and clients.
  • Coordinate with third-party collaborators for PK studies (animal models).

General Lab Contributions

  • Contribute to group activities such as ordering, stocking, and follow-up.
  • Take responsibility for ordering lab supplies and keeping the lab stocked and in good order.
  • Work closely with other biology groups involved in screening, cell biology, protein biology, and ADME.
  • Offer integrated drug discovery support alongside chemistry for multiple client-based projects.

Job Requirements

Experience and Skills

  • Minimum 2-4 years of working experience with LC-MS/MS, HPLC, bio-analytical studies, etc.
  • Hands-on/practical exposure to general biotech laboratory equipment (cell-culture lab, in-vitro and ADME lab).
  • Theoretical understanding and practical work experience with:
    • Cell culture techniques (established cell lines).
    • ADME assays (microsomal stability, plasma stability, solubility, permeability, CYP inhibition assays, plasma protein binding assays, etc.).
  • High self-motivation to initiate projects and work independently under aggressive deadlines.
  • Strong technical knowledge with exceptional attention to detail.
  • Excellent understanding and knowledge of laboratory tools, techniques, methods, and underlying principles.

Personal Qualities and Interpersonal Skills

  • Ability to overcome technical challenges and exercise sound judgment under pressure.
  • Excellent personal rapport and ability to engender trust and respect.
  • Ability to work well as part of a small focused team and build relationships.
  • Exceptional communication skills and ease in interaction with all stakeholders.
  • Infectious enthusiasm for life, work, and making a difference in the world.
  • Bright, friendly, and flexible personality with agility to switch between different skill sets.
  • Exceptional organizational skills that thrive in a fast-paced and vibrant team environment.
  • Positivity, focus, and a winning mentality allied with kindness.
  • Curiosity, energy, creativity, and bravery with a strong desire to help build the o2h culture.