Principal Scientist – Oncology Biology (La Jolla, CA)
Job Summary:
Novartis is hiring a Principal Scientist, Biology for its Oncology Biotherapeutics division at its La Jolla, California site. This role offers a chance to lead innovative drug discovery initiatives in oncology, especially in induced proximity drug discovery and targeted protein degradation. With a competitive compensation package ranging from $119,700 to $222,300 per year, this full-time, on-site role is ideal for scientists ready to advance cutting-edge oncology research in a collaborative environment.
Key Responsibilities:
Lead oncology drug discovery programs from concept through IND-enabling studies
Plan and conduct in vitro and in vivo experiments to support drug development
Identify and validate molecular targets suitable for induced proximity approaches
Lead and mentor bench-facing scientists to achieve scientific milestones
Collaborate across functional teams to execute high-impact oncology research
Present research progress and strategic insights to leadership and governance teams
Drive scientific innovation and cross-functional discovery initiatives
Required Skills & Qualifications:
Ph.D., M.S., or B.S. in Molecular Biology, Cancer Biology, Biochemistry, or related discipline
5–8+ years of relevant industry experience
Proven leadership in bench-facing research and scientific program delivery
Strong knowledge of cell biology, biochemistry, chemical biology, and chemical genomics
Experience in IND documentation and oncology-focused drug discovery
Highly organized and quality-driven with excellent communication skills
Perks & Benefits:
Competitive salary: $119,700 – $222,300 per year
Potential for sign-on bonus, equity awards, and performance-based incentives
Comprehensive benefits: medical, dental, vision, 401(k) with match
Paid time off including vacation, sick leave, and parental leave
Professional development and cross-functional collaboration opportunities
Company Description:
Novartis Institutes for BioMedical Research (NIBR) is a global leader in advancing science for patient impact. With state-of-the-art research centers and a deep commitment to transformative oncology therapies, Novartis is shaping the future of medicine through breakthrough innovations and strategic scientific leadership.
Work Mode:
On-site – La Jolla, California
Call to Action:
Ready to lead the next generation of cancer research? Join Novartis and contribute to oncology drug discovery that makes a real difference.
Apply today to become a part of this groundbreaking mission.
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