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Principal Scientist - Medicinal Chemistry

5+ years
Not Disclosed
10 Nov. 24, 2024
Job Description
Job Type: Full Time Remote Education: MSc./M. Pharm/PhD Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

The job description details a Principal Scientist position in Medicinal Chemistry at Organon R&D Finland, focusing on supporting drug discovery and development projects, particularly in women's health. Below is a summary:


Position Overview:

The Principal Scientist will play a pivotal role in drug discovery, contributing medicinal chemistry expertise across all phases of drug research, from target identification to non-clinical candidate selection. The position involves leading medicinal chemistry projects, designing and optimizing novel molecules, and managing partnerships with CROs and academic collaborators.


Key Responsibilities:

  1. Drug Discovery Leadership:
    • Lead medicinal chemistry projects from hit finding to non-clinical candidate selection.
    • Design and optimize novel small molecules for efficacy, safety, and DMPK properties.
    • Contribute to new drug target ideation, evaluation, and validation.
  2. Collaboration & Communication:
    • Manage activities with discovery CROs and academic partners.
    • Liaise with internal and external teams, including chemists, biologists, and pharmacologists.
  3. Technical Contributions:
    • Participate in synthesis planning, route scouting, and scale-up activities.
    • Monitor and evaluate scientific literature and patents.
    • Prepare detailed reports, presentations, and proposals.
  4. Strategic Execution:
    • Support project planning to ensure alignment with priorities and timelines.
    • Contribute to achieving project objectives effectively and efficiently.

Required Education, Experience, and Skills:

  • Educational Background:
    • Ph.D. in Organic Chemistry, Medicinal Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field.
  • Experience:
    • 5+ years of experience in medicinal chemistry within the pharmaceutical industry.
    • Hands-on experience in discovery phases from hit finding to non-clinical candidate nomination.
    • Expertise in evaluating and validating target ideas.
    • Proven track record of publications, including patent inventorship.
  • Technical Skills:
    • Deep understanding of modern synthetic chemistry and analytical techniques (NMR, chromatography, etc.).
    • Proficiency in using scientific software, databases, and applications.
  • Soft Skills:
    • Strong organizational, teamwork, and problem-solving abilities.
    • Effective communication and presentation skills in Finnish and English.
    • Ability to work under deadlines and manage multiple priorities.
  • Personal Attributes:
    • Self-driven, innovative, and attentive to detail.
    • Able to collaborate effectively within multidisciplinary teams.

Additional Information:

  • Location: Organon R&D Finland operates from facilities in Turku and Oulu.
  • Travel: Approximately 25% travel may be required.
  • Relocation & VISA Sponsorship: Not available.
  • Work Arrangement: Standard work week, with flexibility as needed.
  • Employee Status: Regular full-time position.

About Organon:

Organon is a global healthcare company focused on improving lives through innovative health solutions. With a strong emphasis on women's health, biosimilars, and other trusted health products, Organon is committed to scientific excellence and making a meaningful difference.

This role represents an exciting opportunity for experienced medicinal chemists to contribute to impactful research in a collaborative, forward-thinking environment.