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Principal Biostatistician

0-2 years
Not Disclosed
10 May 2, 2025
Job Description
Job Type: Remote Education: B.Sc./M.Sc/B.Pharm/M.Pharm/Life Science Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

 

Job Title:

Principal Biostatistician


Company:

Syneos Health
A fully integrated biopharmaceutical solutions organization supporting the development and commercialization of therapies, Syneos Health operates in over 110 countries with expertise across clinical development, medical affairs, and commercial services.


Location:

India (Remote/Flexible)


Job ID:

25003326


Updated:

May 2, 2025 (Today)


Job Summary:

The Principal Biostatistician serves as a senior statistical leader on projects, mentoring team members and ensuring delivery of high-quality statistical services across the clinical development lifecycle—from study design to final reporting. This role requires deep expertise in statistical analysis, leadership on complex studies or submissions, and effective cross-functional collaboration.


Key Responsibilities:

  • Mentor and train biostatistics staff; lead internal training sessions.

  • Serve as statistical lead across all phases of clinical trial support—from protocol development to CSR.

  • Develop/review Statistical Analysis Plans (SAPs) and mock-ups for TLFs.

  • Ensure quality control and accuracy of statistical deliverables.

  • Oversee programming specs and review annotated CRFs and database design.

  • Lead complex/multi-study projects, submissions, and interact with regulatory agencies.

  • Manage timelines and budgets, identifying out-of-scope work and escalating as needed.

  • Participate in DSMB/DMC activities as voting or non-voting biostatistician.

  • Collaborate with cross-functional teams and contribute to internal meetings.

  • Support business development (e.g., proposals, budgets, bid defense).

  • Ensure compliance with SOPs, ICH guidelines, and documentation standards.


Qualifications:

Required:

  • Graduate degree in Biostatistics or related field.

  • Extensive experience in clinical trials and leadership across projects.

  • Strong SAS programming and statistical design knowledge.

  • Comprehensive knowledge of ICH guidelines and regulatory frameworks.

  • Excellent communication and project management skills.

  • Fluent in English (written and verbal).

Preferred:

  • Experience with regulatory submissions (e.g., FDA, EMA).


About Syneos Health:

Syneos Health has supported 94% of novel FDA drug approvals and 95% of EMA-authorized products over the last five years. With a global presence and mission to accelerate therapy delivery, the company values innovation, collaboration, and inclusion.