Join Amgen’s Mission of Serving Patients
At Amgen, you’re part of something bigger. Our shared mission—to serve patients living with serious illnesses—drives everything we do. Since 1980, we’ve helped pioneer the world of biotech, focusing on four therapeutic areas: Oncology, Inflammation, General Medicine, and Rare Disease. We reach millions of patients each year, and as a member of the Amgen team, you’ll help make a lasting impact on the lives of patients while advancing your own career.
What You Will Do
Let’s change the world together! In this internship, you will work within the Pharmacokinetics and Drug Metabolism (PKDM) group at Amgen to develop innovative drug discovery techniques supporting multiple therapeutic programs in research and development. Your work will focus on drug-target engagement, mechanisms of action, and discovering biomarkers to facilitate drug development.
The intern will be responsible for performing cell culture, sample preparation, reagent screening, LC-MS/MS method development, and data analysis. You’ll also keep an electronic laboratory notebook and communicate results with project teams.
The PKDM department is dedicated to discovering and developing novel, effective, and safe medicines. In close partnership with medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology, and regulatory teams, you will help design promising clinical candidates, conduct preclinical studies, support clinical evaluations, and contribute to IND and NDA filings.
You will work with a team to develop and optimize untargeted proteomics workflows to identify unknown protein adducts from small molecule drugs and their metabolites. A targeted LCMS workflow will also be developed to validate and quantify these adducts. The intern will implement these workflows into early drug discovery programs to provide mechanistic insights for decision-making. Key responsibilities include:
What We Expect of You
We are looking for a motivated individual with a strong proteomics background. Here’s what we expect:
What You Can Expect of Us
Amgen is committed to your professional and personal growth. With competitive benefits and a collaborative culture, we’ll support your journey every step of the way.
Apply Now
For an internship that challenges and inspires, join us! Keyword: R-199630.
Application Deadline:
Amgen does not have a set deadline for this position. We will accept applications until we find the right candidate.
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