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Director Biostatistics

0-2 years
Not Disclosed
10 May 1, 2025
Job Description
Job Type: Full Time Hybrid Education: MS/MA Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

 

Job Title: Director, Biostatistics

Location: San Francisco Bay Area (Hybrid)
Company: Confidential (via Penfield Search Partners Ltd)
Employment Type: Full-time
Salary: $1/yr – $2/yr (indicative / placeholder range)
Industry: Biopharmaceutical / Clinical Research / Oncology


Company Overview

A clinical-stage biopharmaceutical company specializing in oncology is seeking an experienced Director of Biostatistics to lead statistical strategy and execution across all phases of global clinical trials. This hybrid role offers a highly competitive compensation package and the opportunity to work in a dynamic, science-driven organization.


Position Summary

The Director of Biostatistics will provide leadership in statistical design, analysis, regulatory strategy, and data management for clinical trials, with a focus on oncology. The role includes cross-functional collaboration, regulatory interaction, and oversight of CROs, with a strong emphasis on CDISC standards and FDA/EU compliance.


Key Responsibilities

  • Lead statistical design and analysis for clinical trials across all phases.

  • Develop and implement statistical strategies and standards for the department.

  • Review protocols, SAPs, case report forms, and ensure sound trial methodology.

  • Analyze data and collaborate with clinical teams on reporting and publications.

  • Oversee development and validation of integrated safety and efficacy summaries.

  • Represent the biostatistics function in regulatory interactions (FDA/EU).

  • Manage and evaluate CROs and vendors regarding deliverables, budgets, and quality.

  • Contribute to RFPs and scope-of-work documentation.

  • Ensure compliance with industry and regulatory standards including CDISC, FDA guidelines.


Required Qualifications

  • PhD in Biostatistics/Statistics with 8+ years OR MS/MA with 11+ years of industry experience.

  • Extensive background in clinical trials, preferably in oncology and within biotech/pharma.

  • Strong knowledge of CDISC (SDTM/ADaM), FDA/EU statistical regulations.

  • Proficiency in SAS and R.

  • Demonstrated experience interacting with health authorities.

  • Effective leadership and cross-functional communication skills.